Description

Piperazine, 1-Acetyl-2-Methoxy-, (S)- (9Ci) is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where stereochemical control is critical for efficacy and safety. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Serves as a building block in catalytic asymmetric reactions to introduce the (S)-configured piperazine moiety into target molecules.
• Agrochemical Research: Used in the synthesis of advanced, enantiomerically pure pesticides and herbicides to enhance selectivity and reduce environmental impact.
• Ligand and Catalyst Development: Employed in the design and preparation of novel chiral ligands and organocatalysts for use in stereoselective transformations.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in synthetic organic and medicinal chemistry.

Basic Information

Product Name	Piperazine, 1-Acetyl-2-Methoxy-, (S)- (9Ci)
CAS No.	184832-00-6
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(S)-1-Acetyl-2-methoxypiperazine; (S)-2-Methoxy-1-acetylpiperazine; 1-Acetyl-2-methoxy-(S)-piperazine; (S)-N-Acetyl-2-methoxypiperazine; 1-Acetyl-2-methoxy-(S)-piperazine (9CI); 2-Methoxy-1-(1-oxoethyl)-(S)-piperazine; (S)-1-(2-Methoxypiperazin-1-yl)ethanone
EINECS	Contact for details

Quality Control

Our Piperazine, 1-Acetyl-2-Methoxy-, (S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.