Description

1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-Quinolinyl)Ethenyl]Phenyl]-3-Hydroxypropyl]Phenyl]Acetate is a high-purity, synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical advanced pharmaceutical intermediate or a reference standard for analytical purposes. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in research targeting inflammation and immune modulation.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate biological pathways and receptor interactions.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-Quinolinyl)Ethenyl]Phenyl]-3-Hydroxypropyl]Phenyl]Acetate
CAS No.	184764-13-4
Molecular Formula	C28H24ClNO3
Molecular Weight	457.95 g/mol
Synonyms	Montelukast Impurity; Montelukast Related Compound; (1E)-1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]ethanone; 1-[2-[(3S)-3-[3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl]-3-hydroxypropyl]phenyl]ethanone; (S)-1-(2-(3-(3-((E)-2-(7-Chloro-2-quinolinyl)vinyl)phenyl)-3-hydroxypropyl)phenyl)ethanone; 184764-13-4; Montelukast Acetate Derivative
EINECS	Contact for details

Quality Control

Our 1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-Quinolinyl)Ethenyl]Phenyl]-3-Hydroxypropyl]Phenyl]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC purity assay and identity confirmation (IR, NMR, MS), to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.