Description

5-Oxo-6,6,6-Trifluorohexanoic Acid is a high-value fluorinated organic acid building block, essential for introducing the trifluoroethyl ketone moiety into complex molecular architectures. Its unique structure makes it a critical intermediate for synthesizing advanced pharmaceuticals and agrochemicals, where the fluorine atoms enhance metabolic stability and bioavailability. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl ketone functional group for enhanced drug properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorine substitution improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and fluorine chemistry.
• Material Science Research: Employed in the development of fluorinated polymers and advanced materials with specific thermal, chemical, or surface properties.
• Organic Synthesis Building Block: A versatile reagent for constructing complex organic molecules in medicinal chemistry and process research.

Basic Information

Product Name	5-Oxo-6,6,6-Trifluorohexanoic Acid
CAS No.	184157-09-3
Molecular Formula	C6H7F3O3
Molecular Weight	184.11 g/mol
Synonyms	6,6,6-Trifluoro-5-oxohexanoic acid; 5-Oxo-6,6,6-trifluorohexanoic acid; 6,6,6-Trifluorolevulinic acid; 5-Oxo-6,6,6-trifluorocaproic acid; 184157-09-3; Hexanoic acid, 5-oxo-6,6,6-trifluoro-; 6,6,6-Trifluoro-5-oxo-hexanoic acid
EINECS	Contact for details

Quality Control

Our 5-Oxo-6,6,6-Trifluorohexanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is sensitive to strong bases and fluorides; keep away from incompatible materials. Keep container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.