Description

Celecoxib is a highly selective cyclooxygenase-2 (COX-2) inhibitor, a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. It is valued for its potent anti-inflammatory and analgesic properties with a reduced risk of gastrointestinal side effects compared to traditional NSAIDs. This active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry developing treatments for conditions such as osteoarthritis, rheumatoid arthritis, and acute pain.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for pain and inflammation management.
• Osteoarthritis Treatment: Formulated into capsules or tablets for long-term management of joint pain and stiffness.
• Rheumatoid Arthritis Therapy: Used in medications to reduce inflammation and slow joint damage.
• Acute Pain Relief: Incorporated into formulations for the short-term treatment of postoperative or injury-related pain.
• Drug Development & Research: Serves as a reference standard and key intermediate in preclinical and clinical research for novel NSAIDs.
• Generic Drug Manufacturing: Critical for producing cost-effective generic versions of branded celecoxib medications for global markets.

Basic Information

Product Name	Celecoxib
CAS No.	184007-95-2
Molecular Formula	C17H14F3N3O2S
Molecular Weight	381.37 g/mol
Synonyms	4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; SC-58635; Celebrex (Trade Name); YM-177; COX-2 Inhibitor II; Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-
EINECS	Contact for details

Quality Control

Our Celecoxib is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Each batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and quality assurance for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.15% Total impurities: ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.