Description

1-tert-Butyl 3-Ethyl Piperazine-1,3-Dicarboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the development of novel pharmaceutical intermediates, particularly in the creation of complex molecules with targeted biological activity. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require complex piperazine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.
• Peptidomimetics and Bioactive Molecule Design: The protected carboxylate groups make it suitable for constructing peptide analogs and other bioactive molecules.

Basic Information

Product Name	1-tert-Butyl 3-Ethyl Piperazine-1,3-Dicarboxylate
CAS No.	183742-29-2
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	1-Boc-3-ethyl piperazine-1,3-dicarboxylate; tert-Butyl 3-ethoxycarbonylpiperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-(ethoxycarbonyl)piperazine; 3-Ethyl 1-tert-butyl piperazine-1,3-dicarboxylate; N-Boc-N'-ethoxycarbonylpiperazine; Piperazine-1,3-dicarboxylic acid, 1-(1,1-dimethylethyl) 3-ethyl ester; 1,3-Piperazinedicarboxylic acid, 1-(1,1-dimethylethyl) 3-ethyl ester; BOC-Pip(COOEt)-OH (protected form).
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 3-Ethyl Piperazine-1,3-Dicarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is accompanied by a comprehensive Certificate of Analysis (COA). The COA provides detailed results from analytical techniques including HPLC, NMR, and mass spectrometry, confirming identity, purity, and the absence of critical impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.