Description

17(S)-Hete is a specialized hydroxy fatty acid epoxide, a bioactive lipid mediator derived from arachidonic acid metabolism. This compound is of significant interest for its role as a signaling molecule in various physiological and pathological processes, particularly in the fields of inflammation and vascular biology. It serves as a critical research chemical for pharmaceutical R&D, biotechnology, and advanced life science studies, enabling investigations into eicosanoid pathways and therapeutic target validation.

Application

• Pharmaceutical Research & Development: A key reference standard and intermediate for studying inflammation, angiogenesis, and cardiovascular diseases.
• Biochemical Assay Development: Used as a precise calibrant and control in ELISA, LC-MS/MS, and other analytical methods for eicosanoid profiling.
• Cell Signaling Studies: Essential for in vitro and in vivo research on the biological activities of epoxy-oxylipins and their receptor interactions.
• Academic & Institutional Research: Supports fundamental research in biochemistry, pharmacology, and molecular biology at universities and government labs.
• Biomarker Discovery: Utilized in metabolomics and lipidomics research to identify and quantify lipid-based biomarkers.
• Contract Research Organizations (CROs): Supplied as a high-purity material for client-sponsored drug discovery and toxicology studies.

Basic Information

Product Name	17(S)-Hete
CAS No.	183509-25-3
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	17(S)-Hydroxyeicosatetraenoic acid; 17(S)-HETE; 17S-HETE; (17S)-HETE; 17(S)-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; 17(S)-Hydroxyarachidonic acid; 17-HETE (S-isomer); 17S-Hydroxyeicosatetraenoic acid
EINECS	Contact for details

Quality Control

Every batch of 17(S)-Hete is manufactured and analyzed under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with research-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen), as the compound is easily oxidized and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98% (17S-isomer)
Solubility	Soluble in ethanol, DMSO, and dimethyl formamide

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.