Description

(5Z,8Z,11Z,14Z,16R)-16-Hydroxyicosa-5,8,11,14-Tetraenoic Acid is a specialized, high-purity hydroxy fatty acid derivative of arachidonic acid. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential intermediate or analog in the study of eicosanoid signaling pathways and lipid metabolism. It is primarily utilized by research institutions and development laboratories in the life sciences sector for advanced studies in inflammation, cell signaling, and as a reference standard.

Application

• Biochemical Research: Used as a key intermediate or reference standard in the study of lipoxygenase and cytochrome P450 pathways.
• Pharmaceutical R&D: Serves as a building block or analytical standard in the development of novel therapeutics targeting inflammatory and metabolic disorders.
• Cell Signaling Studies: Employed to investigate the biological activity and metabolism of hydroxy-eicosatetraenoic acids (HETEs) and related lipid mediators.
• Analytical Chemistry: Utilized as a high-purity certified reference material (CRM) for method development and calibration in chromatographic analysis (HPLC, LC-MS).
• Enzymology: Acts as a substrate or product in enzymatic assays for studying the activity of specific oxygenases and hydroxylases.

Basic Information

Product Name	(5Z,8Z,11Z,14Z,16R)-16-Hydroxyicosa-5,8,11,14-Tetraenoic Acid
CAS No.	183509-22-0
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	16(R)-HETE; 16(R)-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 16R-HETE; 16(R)-Hydroxyarachidonic Acid; (16R)-16-Hydroxyicosa-5,8,11,14-tetraenoic Acid; 16R-Hydroxyeicosatetraenoic Acid; 5,8,11,14-Eicosatetraenoic acid, 16-hydroxy-, (5Z,8Z,11Z,14Z,16R)-
EINECS	Contact for details

Quality Control

Every batch of (5Z,8Z,11Z,14Z,16R)-16-Hydroxyicosa-5,8,11,14-Tetraenoic Acid is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA), detailing results from HPLC, NMR, and other relevant tests, is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.