Description

1-Piperazinecarboxylic Acid,4-Formyl-,1,1-Dimethylethyl Ester is a high-value, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality, featuring both a formyl group and a Boc-protected secondary amine, enabling precise and sequential modifications for complex molecule construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs), catalysts, and specialized ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the piperazine scaffold contributes to biological activity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The protected amine and aldehyde functionalities are instrumental in constructing peptide analogs and constrained scaffolds for medicinal chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high-purity, functionalized heterocycles.

Basic Information

Product Name	1-Piperazinecarboxylic Acid,4-Formyl-,1,1-Dimethylethyl Ester
CAS No.	183383-30-4
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	tert-Butyl 4-formylpiperazine-1-carboxylate; 1-Boc-4-formylpiperazine; 4-Formyl-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; N-Boc-4-formylpiperazine; Boc-4-formylpiperazine; 1-(tert-Butoxycarbonyl)-4-formylpiperazine; 4-Formylpiperazine-1-carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid,4-Formyl-,1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.