Description

2,5-Piperazinedione, 3,6-Bis(Chloromethyl)- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecular architectures, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold for the synthesis of novel piperazine and diketopiperazine-based drug candidates, including potential kinase inhibitors and other biologically active molecules.
• Peptidomimetic Research: Used in the design and construction of peptidomimetics and constrained peptides due to its diketopiperazine core, which can mimic peptide turn structures.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the synthesis of specialty polymers, such as polyamides or polymers with tailored degradation profiles.
• Agrochemical Synthesis: Employed as a building block in the development of new herbicides, fungicides, or insecticides with novel modes of action.
• Ligand and Catalyst Development: Utilized to create complex chelating ligands for metal catalysis or molecular recognition applications.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function or protein-protein interactions within biological systems.

Basic Information

Product Name	2,5-Piperazinedione, 3,6-Bis(Chloromethyl)- (9Ci)
CAS No.	182878-29-1
Molecular Formula	C6H8Cl2N2O2
Molecular Weight	211.05 g/mol
Synonyms	3,6-Bis(chloromethyl)-2,5-piperazinedione; 3,6-Bis(chloromethyl)piperazine-2,5-dione; 1,4-Diazacyclohexane-2,5-dione, 3,6-bis(chloromethyl)-; Bis(chloromethyl)diketopiperazine; DKP-BCM; 2,5-Diketopiperazine-1,4-diacetic acid dichloride (derivative)
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione, 3,6-Bis(Chloromethyl)- is produced under strict quality management protocols. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), impurity profile, and physical characteristics are provided and available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.