Description

3-(3-(3,4-Dichlorophenyl)Piperidin-3-Yl)Propan-1-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-based structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and generic drugs, where precise molecular architecture and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in neurological and psychiatric research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for APIs under preclinical and clinical investigation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for commercial manufacturing.
• Reference Standard: Serves as a high-purity standard for analytical method development and quality control in regulatory submissions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-(3-(3,4-Dichlorophenyl)Piperidin-3-Yl)Propan-1-Ol
CAS No.	182621-51-8
Molecular Formula	C14H19Cl2NO
Molecular Weight	288.21 g/mol
Synonyms	3-[3-(3,4-Dichlorophenyl)piperidin-3-yl]propan-1-ol; 1-Propanol, 3-[3-(3,4-dichlorophenyl)-3-piperidinyl]-; 3-(3-(3,4-Dichlorophenyl)piperidin-3-yl)propanol; 182621-51-8; 3-(3-(3,4-Dichlorophenyl)-3-piperidinyl)-1-propanol
EINECS	Contact for details

Quality Control

Our 3-(3-(3,4-Dichlorophenyl)Piperidin-3-Yl)Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.