Description

1,2-Cyclohexanediol, 1-(1-Piperidinylmethyl)-, cis- (9Ci) is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring both a diol and a piperidinylmethyl moiety, makes it a valuable precursor for the development of complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a key scaffold for constructing active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides, herbicides, and fungicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a backbone for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-purity, complex organic molecules for various industrial applications.
• Academic & Industrial R&D: A valuable reagent for methodological research in organic chemistry, exploring new synthetic routes and reaction mechanisms.

Basic Information

Product Name	1,2-Cyclohexanediol, 1-(1-Piperidinylmethyl)-, cis- (9Ci)
CAS No.	182277-69-6
Molecular Formula	C12H23NO2
Molecular Weight	213.32 g/mol
Synonyms	cis-1-(Piperidin-1-ylmethyl)cyclohexane-1,2-diol; (1R,2S)-1-[(Piperidin-1-yl)methyl]cyclohexane-1,2-diol; 1,2-Cyclohexanediol, 1-(piperidinylmethyl)-, cis-; cis-1-(1-Piperidinylmethyl)-1,2-cyclohexanediol; 182277-69-6; (1R,2S)-1-(Piperidin-1-ylmethyl)cyclohexane-1,2-diol; 1-(Piperidin-1-ylmethyl)cyclohexane-1,2-diol (cis isomer)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), tailored to meet the specific needs of research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system ensures traceability and consistency for every batch supplied.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.