Description

1-Benzyl-4-Boc-Piperazine-2-Carboxylic Acid is a high-purity, protected piperazine derivative that serves as a critical building block in modern synthetic chemistry. This compound is essential for the efficient synthesis of complex molecules, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly those containing piperazine or piperidine scaffolds.
• Peptidomimetic Research: Used to introduce constrained amino acid analogs into peptide chains to enhance stability and biological activity.
• Medicinal Chemistry: Serves as a versatile building block for constructing combinatorial libraries and exploring structure-activity relationships (SAR).
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Agrochemical Development: Potential intermediate in the synthesis of novel crop protection agents and herbicides.

Basic Information

Product Name	1-Benzyl-4-Boc-Piperazine-2-Carboxylic Acid
CAS No.	181956-25-2
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	1-Benzyl-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid; 4-Boc-1-benzylpiperazine-2-carboxylic acid; tert-Butyl 1-benzyl-2-carboxypiperazine-1-carboxylate; 1-Benzyl-4-(tert-butyloxycarbonyl)piperazine-2-carboxylic acid; 1-Boc-4-benzylpiperazine-2-carboxylic acid; N-Boc-N'-benzylpiperazine-2-carboxylic acid; (1-Benzyl-4-tert-butoxycarbonyl-piperazin-2-yl)-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-Boc-Piperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.