Description

Methyl 4-Benzylpiperazine-2-Carboxylate is a high-purity, versatile piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a valuable building block for the development of novel bioactive molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating complex chemical libraries and active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Building block for developing novel pesticides, herbicides, and plant growth regulators.
• Chemical Synthesis: Versatile scaffold for constructing complex piperazine-based heterocycles and fine chemicals.
• Academic & R&D: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds.
• Ligand & Catalyst Development: Potential precursor for chelating agents or organocatalysts in asymmetric synthesis.

Basic Information

Product Name	Methyl 4-Benzylpiperazine-2-Carboxylate
CAS No.	181955-94-2
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	Methyl 4-benzyl-2-piperazinecarboxylate; 4-Benzyl-2-piperazinecarboxylic acid methyl ester; Methyl 4-benzylpiperazine-2-carboxylate; 2-Piperazinecarboxylic acid, 4-benzyl-, methyl ester; 181955-94-2; Methyl 4-benzyl-1-piperazinecarboxylate (isomer); 4-Benzylpiperazine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Benzylpiperazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications such as assay (by HPLC), identity (IR, NMR), and impurity profiles. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.