Description

(2R)-2-[(Ethoxycarbonyl)Methyl]-4-Methylpentanoic Acid is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable building block for the production of complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, enzyme modulators, and other complex drug candidates.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective reactions to construct molecules with high enantiomeric purity.
• Peptidomimetics Research: Serves as a constrained amino acid analog for the development of novel peptide-based therapeutics and diagnostic agents.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides where specific stereochemistry is crucial for activity.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands and organocatalysts used in homogeneous catalysis.
• Academic and R&D Laboratories: Employed in methodological studies and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	(2R)-2-[(Ethoxycarbonyl)Methyl]-4-Methylpentanoic Acid
CAS No.	181289-10-1
Molecular Formula	C10H18O4
Molecular Weight	202.25 g/mol
Synonyms	(R)-2-(Ethoxycarbonylmethyl)-4-methylpentanoic acid; (2R)-2-(Carbethoxymethyl)-4-methylpentanoic acid; (R)-2-[(Ethoxycarbonyl)methyl]-4-methylpentanoic acid; 4-Methyl-2-[(ethoxycarbonyl)methyl]pentanoic acid, (2R)-; (R)-Ethyl 2-(1-carboxy-3-methylbutyl)acetate; D-2-[(Ethoxycarbonyl)methyl]-4-methylpentanoic acid; (2R)-2-(2-Ethoxy-2-oxoethyl)-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our (2R)-2-[(Ethoxycarbonyl)Methyl]-4-Methylpentanoic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to meet the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.