Description

1H-Indeno[1,2-B]Pyrazine,2,3,4,4A,9,9A-Hexahydro-1-Methyl-,cis-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex, fused polycyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. Research and development teams in the pharmaceutical and biotechnology sectors need this precise chemical scaffold to drive innovation in drug discovery programs. Its defined stereochemistry and purity are essential for ensuring reproducible outcomes in complex synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new chemical space.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead molecules.
• Process Chemistry Development: Acts as a standard or starting material for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	1H-Indeno[1,2-B]Pyrazine,2,3,4,4A,9,9A-Hexahydro-1-Methyl-,cis-(9Ci)
CAS No.	181034-51-5
Molecular Formula	C12H14N2
Molecular Weight	186.25 g/mol
Synonyms	cis-1-Methyl-1,2,3,4,4a,9a-hexahydroindeno[1,2-b]pyrazine; 1-Methyl-1,2,3,4,4a,9a-hexahydroindeno[1,2-b]pyrazine (cis-); Indeno[1,2-b]pyrazine, 1,2,3,4,4a,9a-hexahydro-1-methyl-, cis-; cis-1-Methylhexahydroindeno[1,2-b]pyrazine; 181034-51-5; (4aR,9aS)-1-Methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[1,2-b]pyrazine; (cis)-1-Methyl-1,2,3,4,4a,9a-hexahydroindeno[1,2-b]pyrazine
EINECS	Contact for details

Quality Control

Our 1H-Indeno[1,2-B]Pyrazine,2,3,4,4A,9,9A-Hexahydro-1-Methyl-,cis-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and process development. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment. We support compliance with relevant guidelines and can supply material suitable for use under cGMP standards for non-clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.