Description

1H-Indeno[1,2-B]Pyrazine,2,3,4,4A,9,9A-Hexahydro-1-Methyl-,trans-(9Ci) is a high-purity, complex heterocyclic compound with a fused indene-pyrazine structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the construction of sophisticated molecular architectures for research and development, particularly in the pharmaceutical sector. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas requiring complex heterocyclic cores.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities and optimize lead compounds.
• Process Chemistry Development: Serves as a pivotal intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents and pesticides that utilize nitrogen-containing heterocycles.
• Material Science Precursor: Can be investigated as a monomer or precursor for specialty polymers and organic electronic materials due to its rigid, fused-ring system.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	1H-Indeno[1,2-B]Pyrazine,2,3,4,4A,9,9A-Hexahydro-1-Methyl-,trans-(9Ci)
CAS No.	181034-50-4
Molecular Formula	C12H14N2
Molecular Weight	186.25 g/mol
Synonyms	trans-1-Methyl-1,2,3,4,4a,9,9a,10-octahydroindeno[1,2-b]pyrazine; 1-Methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[1,2-b]pyrazine, trans-; trans-1-Methyl-1,2,3,4,4a,9,9a,10-octahydroindeno[1,2-b]pyrazine; 1H-Indeno[1,2-b]pyrazine, 2,3,4,4a,9,9a-hexahydro-1-methyl-, trans-; (4aR,9aS)-1-Methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[1,2-b]pyrazine; (trans)-1-Methyl-1,2,3,4,4a,9,9a,10-octahydroindeno[1,2-b]pyrazine; 181034-50-4
EINECS	Contact for details

Quality Control

Our production of 1H-Indeno[1,2-B]Pyrazine,2,3,4,4A,9,9A-Hexahydro-1-Methyl-,trans-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment, and we support custom synthesis under specific quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.