Description

tert-Butyl (2R,6S)-2,6-Dimethylpiperazine-1-Carboxylate is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, including potential central nervous system (CNS) agents and antiviral compounds.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring high stereochemical control.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	tert-Butyl (2R,6S)-2,6-Dimethylpiperazine-1-Carboxylate
CAS No.	180975-66-0
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(2R,6S)-1-Boc-2,6-Dimethylpiperazine; (2R,6S)-1-(tert-Butoxycarbonyl)-2,6-dimethylpiperazine; (2R,6S)-2,6-Dimethylpiperazine-1-carboxylic acid tert-butyl ester; 1-N-Boc-(2R,6S)-2,6-dimethylpiperazine; tert-Butyl (2R,6S)-2,6-dimethyl-1-piperazinecarboxylate; (2R,6S)-1-Boc-2,6-DMP; (2R,6S)-2,6-Dimethyl-1-Boc-piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl (2R,6S)-2,6-Dimethylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.