Description

2-Butenoicacid,4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-,(2E)-(9Ci) is a high-purity, protected amino acid derivative featuring a reactive α,β-unsaturated ester moiety. This compound serves as a critical chiral building block for the synthesis of complex organic molecules, enabling precise control over stereochemistry and molecular architecture. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams developing novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide mimetics and small molecule drugs.
• Peptide Chemistry: Used for the controlled introduction of dehydroamino acid residues into peptide chains to modify conformation and biological activity.
• Medicinal Chemistry: Serves as a versatile scaffold for constructing libraries of compounds in structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Employed as a substrate in catalytic reactions to create new carbon-carbon and carbon-heteroatom bonds with high enantioselectivity.
• Chemical Biology: Utilized in the synthesis of probes and labeled compounds for studying biological pathways and protein interactions.
• Advanced Material Precursor: Potential use in synthesizing specialized monomers for high-performance polymers.

Basic Information

Product Name	2-Butenoicacid,4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-,(2E)-(9Ci)
CAS No.	180913-22-8
Molecular Formula	C10H15NO4
Molecular Weight	213.23 g/mol
Synonyms	(2E)-4-[(tert-Butoxycarbonyl)amino]-2-butenoic acid; (E)-4-((tert-Butoxycarbonyl)amino)but-2-enoic acid; Boc-DebA-OH; N-Boc-4-amino-(E)-crotonic acid; N-(tert-Butoxycarbonyl)-4-amino-(E)-crotonic acid; 4-[(tert-Butoxycarbonyl)amino]-2-butenoic acid, (E)-; 4-(Boc-amino)-2-butenoic acid, (E)-
EINECS	Contact for details

Quality Control

Our 2-Butenoicacid,4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-,(2E)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and chiral purity analysis to ensure identity, potency, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry, well-ventilated area. This material is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.