Description

tert-Butyl 4-(2-tert-Butoxy-2-Oxoethyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, bifunctional scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing piperazine or morpholine cores.
• Medicinal Chemistry: Used in research for constructing novel drug candidates, leveraging its two orthogonal protecting groups for selective functionalization.
• Agrochemical Synthesis: Intermediate in the development of advanced crop protection agents and pesticides.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal complexation.
• Polymer Chemistry: Can be utilized as a monomer or chain extender in the synthesis of specialty polyamides or polymers with specific functional groups.
• Chemical Biology Probes: Foundation for creating tagged molecules or probes used in biochemical and cellular studies.

Basic Information

Product Name	tert-Butyl 4-(2-tert-Butoxy-2-Oxoethyl)Piperazine-1-Carboxylate
CAS No.	180576-04-9
Molecular Formula	C15H28N2O4
Molecular Weight	300.40 g/mol
Synonyms	1-Boc-4-(2-tert-butoxy-2-oxoethyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-tert-butoxy-2-oxoethyl)piperazine; 4-(2-tert-Butoxy-2-oxoethyl)piperazine-1-carboxylic acid tert-butyl ester; 2-[4-(tert-Butoxycarbonyl)piperazin-1-yl]acetic acid tert-butyl ester; tert-Butyl 4-(carboxymethyl)piperazine-1-carboxylate, ditert-butyl ester; BOC-Piperazine-CH2COOtBu; Piperazine-1-carboxylic acid, 4-(2-tert-butoxy-2-oxoethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-tert-Butoxy-2-Oxoethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.