Description

Phenol, 2-[[(2-Phenyl-3-Piperidinyl)Amino]Methyl]-4-[5-(Trifluoromethyl)-1H-Tetrazol-1-Yl]-, (2S-Cis)- is a high-purity, structurally complex organic compound featuring a phenol core integrated with piperidine and a trifluoromethyl tetrazole moiety. This compound is of significant value as a key pharmaceutical intermediate or advanced building block for medicinal chemistry research and development. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, especially in CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique pharmacophore combination.
• API Synthesis: Employed in the development and scale-up of potential Active Pharmaceutical Ingredients (APIs) requiring a specific stereochemical configuration (2S-cis).
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study specific enzyme or receptor interactions in research settings.
• Fine Chemical Production: Acts as a specialized precursor for the manufacture of other high-value, complex organic molecules.

Basic Information

Product Name	Phenol, 2-[[(2-Phenyl-3-Piperidinyl)Amino]Methyl]-4-[5-(Trifluoromethyl)-1H-Tetrazol-1-Yl]-, (2S-Cis)-
CAS No.	180574-25-8
Molecular Formula	C20H21F3N6O
Molecular Weight	418.42 g/mol
Synonyms	(2S-cis)-2-[[(2-Phenyl-3-piperidinyl)amino]methyl]-4-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenol; 2-[[(2-Phenyl-3-piperidinyl)amino]methyl]-4-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenol, (2S,3S)-rel-; 1H-Tetrazole, 5-(trifluoromethyl)-, 1-[3-hydroxy-4-[[[(2S,3S)-2-phenyl-3-piperidinyl]amino]methyl]phenyl]-; 180574-25-8; UNII-9G9N1I8F1K; 9G9N1I8F1K; (2S,3S)-2-((2-Phenylpiperidin-3-ylamino)methyl)-4-(5-(trifluoromethyl)-1H-tetrazol-1-yl)phenol
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade products are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2S-cis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.