Description

1-[3-(Trifluoromethyl)Benzoyl]Piperazine is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core and trifluoromethylbenzoyl functional group. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Ligand and Modifier Synthesis: Employed in the creation of specialized ligands for catalysis or molecular modifiers in material science.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Benzoyl]Piperazine
CAS No.	179334-14-6
Molecular Formula	C12H13F3N2O
Molecular Weight	258.24 g/mol
Synonyms	1-[3-(Trifluoromethyl)benzoyl]piperazine; 3-(Trifluoromethyl)benzoylpiperazine; 1-[(3-Trifluoromethyl)benzoyl]piperazine; Piperazine, 1-[(3-(trifluoromethyl)benzoyl]-; α,α,α-Trifluoro-m-toluoylpiperazine; m-(Trifluoromethyl)benzoylpiperazine; 179334-14-6
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Benzoyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.