Description

1-[4-(Trifluoromethyl)Benzoyl]Piperazine is a high-value pharmaceutical intermediate and versatile organic building block. Its core value lies in the trifluoromethyl and benzoylpiperazine motifs, which are critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances activity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and molecular recognition applications.
• Material Science Precursor: Can be utilized in the synthesis of advanced organic materials and functional polymers.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Benzoyl]Piperazine
CAS No.	179334-12-4
Molecular Formula	C12H13F3N2O
Molecular Weight	258.24 g/mol
Synonyms	4-(Trifluoromethyl)benzoylpiperazine; 1-[(4-Trifluoromethyl)benzoyl]piperazine; 1-[4-(Trifluoromethyl)benzoyl]piperazine; α,α,α-Trifluoro-p-toluoylpiperazine; Piperazine, 1-[(4-trifluoromethyl)benzoyl]-; 4-(Trifluoromethyl)benzoic acid piperazide
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethyl)Benzoyl]Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.