Description

1-(2,5-Difluorobenzoyl)Piperazine is a high-purity, specialized organic building block featuring a piperazine ring substituted with a 2,5-difluorobenzoyl group. This compound is critical for research and development in advanced pharmaceutical synthesis, serving as a key intermediate for creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers engaged in the development of fluorinated compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecules for material science and catalysis.
• Bioconjugation & Probe Development: The reactive piperazine nitrogen can be utilized for labeling and bioconjugation applications in diagnostic and biochemical research.

Basic Information

Product Name	1-(2,5-Difluorobenzoyl)Piperazine
CAS No.	179334-11-3
Molecular Formula	C11H12F2N2O
Molecular Weight	226.22 g/mol
Synonyms	1-(2,5-Difluorobenzoyl)piperazine; 2,5-Difluorophenyl(piperazin-1-yl)methanone; N-(2,5-Difluorobenzoyl)piperazine; Piperazine, 1-(2,5-difluorobenzoyl)-; 179334-11-3; AKOS005258212; BDBM50389335; SCHEMBL15505527; ZINC000095909786
EINECS	Contact for details

Quality Control

Our 1-(2,5-Difluorobenzoyl)Piperazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.