Description

4-Piperidinecarboxamide,N,2-Dimethyl-,(2R-Cis)-(9Ci) is a high-purity chiral piperidine derivative, a crucial building block in modern organic synthesis. Its stereochemically defined structure makes it an essential intermediate for the development of novel, targeted active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules, particularly in the areas of central nervous system (CNS) agents and other therapeutic candidates. CAS No. 179022-40-3.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for neurological and psychiatric disorders.
• Asymmetric Synthesis: Used as a building block to introduce the (2R-Cis) configured piperidine moiety into more complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	4-Piperidinecarboxamide,N,2-Dimethyl-,(2R-Cis)-(9Ci)
CAS No.	179022-40-3
Molecular Formula	C8H16N2O
Molecular Weight	156.23 g/mol
Synonyms	(2R,4S)-N,2-Dimethyl-4-piperidinecarboxamide; (2R-cis)-N,2-Dimethyl-4-piperidinecarboxamide; 4-Piperidinecarboxamide, N,2-dimethyl-, (2R-cis)-; N,2-Dimethyl-4-piperidinecarboxamide (2R-cis); (2R,4S)-N,2-Dimethylpiperidine-4-carboxamide; cis-N,2-Dimethyl-4-piperidinecarboxamide; 179022-40-3
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarboxamide,N,2-Dimethyl-,(2R-Cis)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.