Description

4-[3-(Methoxycarbonyl)Phenyl]-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and aromatic ester functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical production.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of novel drug candidates, especially in CNS-active compounds.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in academic and industrial labs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced intermediates.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	4-[3-(Methoxycarbonyl)Phenyl]-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	179003-10-2
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	tert-Butyl 4-[3-(methoxycarbonyl)phenyl]piperazine-1-carboxylate; 1-Boc-4-(3-methoxycarbonylphenyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(3-methoxycarbonylphenyl)piperazine; 4-(3-Carbomethoxyphenyl)-1-piperazinecarboxylic acid tert-butyl ester; 179003-10-2; BOC-3-(Methoxycarbonyl)phenylpiperazine
EINECS	Contact for details

Quality Control

Our production of 4-[3-(Methoxycarbonyl)Phenyl]-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use or produced under quality systems aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.