Description

(3Z)-3-[2-(4-Fluorophenyl)-2-Oxo-Ethylidene]-1-Methyl-Piperazin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazinone structure. This compound is of significant value in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, where precise molecular architecture is critical. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its fluorinated aromatic moiety for enhanced biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the manufacture of specialized, high-value chemicals for various industrial and research applications.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(3Z)-3-[2-(4-Fluorophenyl)-2-Oxo-Ethylidene]-1-Methyl-Piperazin-2-One
CAS No.	178408-19-0
Molecular Formula	C14H15FN2O2
Molecular Weight	262.28 g/mol
Synonyms	1-Methyl-3-[(Z)-2-oxo-2-(4-fluorophenyl)ethylidene]piperazin-2-one; (Z)-3-(2-(4-Fluorophenyl)-2-oxoethylidene)-1-methylpiperazin-2-one; 3-[(Z)-2-(4-Fluorophenyl)-2-oxoethylidene]-1-methyl-2-piperazinone; 1-Methyl-3-[(Z)-[2-oxo-2-(4-fluorophenyl)ethylidene]]-2-piperazinone; 178408-19-0; 4-Fluorophenyl piperazinone derivative
EINECS	Contact for details

Quality Control

Our (3Z)-3-[2-(4-Fluorophenyl)-2-Oxo-Ethylidene]-1-Methyl-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are available upon request, and we can support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled and stored under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.