Description

(3E)-3-[2-(2,4-Dimethylphenyl)-2-Oxo-Ethylidene]-1-Methyl-Piperazin-2- One is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazinone-based structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex biological pathways. It is primarily sought by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical synthesis specialists for its role in creating potent and selective drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• API Development: Serves as a crucial precursor in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor modulation.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	(3E)-3-[2-(2,4-Dimethylphenyl)-2-Oxo-Ethylidene]-1-Methyl-Piperazin-2- One
CAS No.	178408-17-8
Molecular Formula	C15H18N2O2
Molecular Weight	258.32 g/mol
Synonyms	(3E)-3-[(2,4-Dimethylphenyl)(oxo)methylidene]-1-methylpiperazin-2-one; 1-Methyl-3-[(2,4-dimethylphenyl)glyoxylidene]piperazin-2-one; (E)-3-(2-(2,4-Dimethylphenyl)-2-oxoethylidene)-1-methylpiperazin-2-one; 178408-17-8; (3E)-3-[2-(2,4-Dimethylphenyl)-2-oxoethylidene]-1-methyl-2-piperazinone
EINECS	Contact for details

Quality Control

Our (3E)-3-[2-(2,4-Dimethylphenyl)-2-Oxo-Ethylidene]-1-Methyl-Piperazin-2- One is manufactured under strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.