Description

(3Z)-1-Methyl-3-[2-(4-Methylphenyl)-2-Oxo-Ethylidene]Piperazin-2-One CAS NO 178408-16-7 is a specialized heterocyclic organic compound featuring a piperazinone core with a methylphenyl ketone substituent. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Organic Synthesis Building Block: Used in the construction of complex molecules for medicinal chemistry, leveraging its reactive ketone and cyclic amide functionalities.
• Agrochemical Research: Serves as a starting material for the synthesis of novel compounds with potential herbicidal or pesticidal activity.
• Material Science: Investigated for the development of specialty polymers or organic electronic materials due to its conjugated structure.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in heterocyclic chemistry and asymmetric synthesis.

Basic Information

Product Name	(3Z)-1-Methyl-3-[2-(4-Methylphenyl)-2-Oxo-Ethylidene]Piperazin-2-One
CAS No.	178408-16-7
Molecular Formula	C15H18N2O2
Molecular Weight	258.32 g/mol
Synonyms	1-Methyl-3-[(Z)-2-(4-methylphenyl)-2-oxoethylidene]piperazin-2-one; (Z)-1-Methyl-3-(2-(4-methylphenyl)-2-oxoethylidene)piperazin-2-one; 3-[(Z)-2-(4-Methylphenyl)-2-oxoethylidene]-1-methylpiperazin-2-one; 1-Methyl-3-[(Z)-2-oxo-2-(p-tolyl)ethylidene]piperazin-2-one; CAS 178408-16-7; Piperazin-2-one derivative; p-Tolyl ketone piperazinone derivative
EINECS	Contact for details

Quality Control

Our (3Z)-1-Methyl-3-[2-(4-Methylphenyl)-2-Oxo-Ethylidene]Piperazin-2-One is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to support cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to direct light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.