Description

tert-Butyl 4-(Azetidin-3-Yl)Piperazine-1-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block for constructing complex molecular architectures, particularly in the synthesis of bioactive molecules targeting the central nervous system and other therapeutic areas. It is essential for medicinal chemistry research and process development within the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with piperazine and azetidine pharmacophores.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a key starting material for the development and optimization of scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Neuropharmacology Drug Development: Employed in the creation of compounds targeting neurological receptors and pathways.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke chemical synthesis projects requiring high-fidelity building blocks.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological mechanisms.

Basic Information

Product Name	tert-Butyl 4-(Azetidin-3-Yl)Piperazine-1-Carboxylate Hydrochloride
CAS No.	178312-58-8
Molecular Formula	C12H24ClN3O2
Molecular Weight	277.79 g/mol
Synonyms	1-Boc-3-(1-Piperazinyl)azetidine Hydrochloride; tert-Butyl 4-(azetidin-3-yl)piperazine-1-carboxylate HCl; 3-(1-Piperazinyl)-1-azetidinecarboxylic Acid 1,1-Dimethylethyl Ester Hydrochloride; 1-(tert-Butoxycarbonyl)-3-(piperazin-1-yl)azetidine Hydrochloride; 1-Boc-3-piperazinylazetidine Hydrochloride; 3-Piperazin-1-yl-azetidine-1-carboxylic Acid tert-Butyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Azetidin-3-Yl)Piperazine-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.