Description

Morpholine, 4-(3-Azetidinyl)-, Dihydrochloride is a high-purity, nitrogen-containing heterocyclic compound supplied as a dihydrochloride salt. This specialized intermediate is critical for pharmaceutical research and development, offering a versatile scaffold for constructing complex bioactive molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Process Chemistry Development: Serves as a critical raw material for optimizing scalable synthetic routes during process research and development (PR&D) stages.
• Bioconjugation & Probe Synthesis: Employed in the creation of biochemical probes and conjugates for diagnostic and research applications.
• Ligand Synthesis for Catalysis: Used to prepare novel nitrogen-based ligands for transition metal catalysis in fine chemical synthesis.

Basic Information

Product Name	Morpholine, 4-(3-Azetidinyl)-, Dihydrochloride
CAS No.	178312-50-0
Molecular Formula	C7H16Cl2N2O
Molecular Weight	215.12 g/mol
Synonyms	4-(Azetidin-3-yl)morpholine dihydrochloride; 3-Morpholin-4-ylazetidine dihydrochloride; 1-(3-Azetidinyl)-4-morpholine dihydrochloride; Azetidine, 3-(4-morpholinyl)-, dihydrochloride; 3-(Morpholin-4-yl)azetidine dihydrochloride; 4-(Azetidin-3-yl)morpholine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our Morpholine, 4-(3-Azetidinyl)-, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.