Description

Piperazine, 1-(3-Azetidinyl)-4-Methyl-, Dihydrochloride is a high-purity, specialized organic salt used as a critical building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. Pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) need this material for its precise structural features that enable the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting neurological pathways.
• Chemical Synthesis Building Block: Used in organic synthesis to introduce the piperazine-azetidine moiety, which is valuable for modifying the physicochemical properties of lead compounds.
• Research & Development: Essential for medicinal chemistry programs in academic and industrial settings for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals beyond pharmaceuticals.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	Piperazine, 1-(3-Azetidinyl)-4-Methyl-, Dihydrochloride
CAS No.	178311-93-8
Molecular Formula	C8H19Cl2N3
Molecular Weight	228.16 g/mol
Synonyms	1-(3-Azetidinyl)-4-Methylpiperazine Dihydrochloride; 4-Methyl-1-(azetidin-3-yl)piperazine Dihydrochloride; 3-(4-Methylpiperazin-1-yl)azetidine Dihydrochloride; 1-(Azetidin-3-yl)-4-methylpiperazine Dihydrochloride; 4-Methyl-1-(azetidin-3-yl)piperazine Dihydrochloride Salt; Azetidine, 3-(4-methyl-1-piperazinyl)-, dihydrochloride; 1-Methyl-4-(3-azetidinyl)piperazine Dihydrochloride
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3-Azetidinyl)-4-Methyl-, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.