Description

4-Cyclohexylcarbamoylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its core value lies in providing a versatile, nitrogen-rich scaffold with orthogonal protecting groups, enabling precise and efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning their pharmacological properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-infectives.
• Agrochemical Synthesis: Used in the design and production of novel herbicides, fungicides, and insecticides, leveraging its piperazine core for bioactivity.
• Peptidomimetics & Bioactive Molecule Construction: Serves as a constrained dipeptide surrogate or a rigid spacer in the synthesis of peptide analogs and other bioactive compounds.
• Ligand & Catalyst Development: Employed as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Cyclohexylcarbamoylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	177971-60-7
Molecular Formula	C18H33N3O3
Molecular Weight	339.48 g/mol
Synonyms	1-Boc-4-[(cyclohexylcarbamoyl)methyl]piperazine; tert-Butyl 4-[(cyclohexylcarbamoyl)methyl]piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[(cyclohexylamino)oxomethyl]methylpiperazine; 4-[(Cyclohexylcarbamoyl)methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; N-Boc-4-(N'-cyclohexylureidomethyl)piperazine; Piperazine-1-carboxylic acid, 4-[(cyclohexylamino)carbonyl]methyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-Cyclohexylcarbamoylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.