Description

5-tert-Butoxycarbonylamino-Pyrazine-2-Carboxylic Acid Ethyl Ester is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for peptide-mimetic and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Peptidomimetic Research: Used to incorporate pyrazine-based scaffolds into peptide backbones, creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex organic molecules for clients.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	5-tert-Butoxycarbonylamino-Pyrazine-2-Carboxylic Acid Ethyl Ester
CAS No.	177759-80-7
Molecular Formula	C₁₂H₁₉N₃O₄
Molecular Weight	269.30 g/mol
Synonyms	Boc-Amino-Pyrazine-2-Carboxylic Acid Ethyl Ester; Ethyl 5-[(tert-Butoxycarbonyl)amino]pyrazine-2-carboxylate; 5-(Boc-amino)pyrazine-2-carboxylic acid ethyl ester; 5-[(tert-Butoxycarbonyl)amino]pyrazine-2-carboxylic Acid Ethyl Ester; 5-Boc-Amino-2-pyrazinecarboxylic Acid Ethyl Ester; Boc-Pyrazine-AA-OEt; 2-Pyrazinecarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-, ethyl ester
EINECS	Contact for details

Quality Control

Our 5-tert-Butoxycarbonylamino-Pyrazine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for chemicals soluble in strong acid/organic solvent. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.