Description

Cyclobutanecarboxaldehyde, 3-Acetyl-2,2-Dimethyl-, (1R,3S)- (9Ci) CAS NO 177316-72-2 is a high-purity, stereochemically defined chiral building block. This compound matters as a critical intermediate for the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its specific stereochemistry is essential for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel therapeutic agents, particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic methodologies.
• Flavor & Fragrance Chemistry: Potential intermediate for creating complex, high-value odorants and flavor molecules with specific stereochemical notes.
• Material Science: Building block for specialty polymers and advanced organic materials requiring precise molecular geometry.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs (Contract Research Organizations).

Basic Information

Item	Detail
Product Name	Cyclobutanecarboxaldehyde, 3-Acetyl-2,2-Dimethyl-, (1R,3S)- (9Ci)
CAS No.	177316-72-2
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1R,3S)-3-Acetyl-2,2-dimethylcyclobutanecarboxaldehyde; (1R,3S)-3-Acetyl-2,2-dimethyl-1-cyclobutanecarboxaldehyde; (1R,3S)-3-Acetyl-2,2-dimethylcyclobutanecarbaldehyde; 3-Acetyl-2,2-dimethylcyclobutanecarboxaldehyde, (1R,3S)-; (1R,3S)-rel-3-Acetyl-2,2-dimethylcyclobutanecarboxaldehyde; Chiral Cyclobutane Aldehyde Derivative
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarboxaldehyde, 3-Acetyl-2,2-Dimethyl-, (1R,3S)- (9Ci) is produced under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity analysis (HPLC/GC), to ensure compliance with industry standards for advanced intermediates. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This material is easily oxidized; ensure containers are properly sealed after each use to exclude air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.