Description

Polygalasaponin Xxviii is a high-purity, bioactive saponin compound derived from the Polygala species. This specialized phytochemical is valued for its role as a key reference standard and active ingredient in advanced research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and academic research sectors for pharmacological studies, quality control of herbal extracts, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of Polygala tenuifolia extracts and related herbal products in QC/QA laboratories.
• Neuropharmacology Research: Investigated for its potential neuroprotective, antidepressant, and cognitive-enhancing properties in preclinical studies.
• Natural Product Isolation & Identification: Serves as a critical marker compound for the authentication and standardization of botanical raw materials.
• Bioactivity Screening: Employed in high-throughput screening assays to evaluate mechanisms of action and structure-activity relationships (SAR).
• Nutraceutical Formulation: Incorporated into advanced dietary supplement blends targeting cognitive support and stress relief.
• Academic & Clinical Research: Provides a pure compound for mechanistic studies, pharmacokinetic profiling, and toxicity evaluations.

Basic Information

Product Name	Polygalasaponin Xxviii
CAS No.	176182-01-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Polygalasaponin XXVIII; Polygalasaponin 28; Saponin from Polygala tenuifolia; Tenuifolin saponin derivative; 3-O-β-D-glucopyranosyl presenegenin 28-O-β-D-glucopyranosyl-(1→4)-β-D-fucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside
EINECS	Contact for details

Quality Control

Our Polygalasaponin Xxviii is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports your need for reliable and consistent reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a low-humidity environment. For long-term storage, consider desiccants or inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.