Description

C8 L-Threo Ceramide (D18:1/8:0) is a high-purity, synthetic sphingolipid with the CAS number 175892-44-1. This specific ceramide is a critical building block for advanced lipid research and the development of next-generation cosmetic and pharmaceutical formulations. It is essential for researchers and manufacturers in the cosmetics, dermatology, and life science industries who require precise, well-defined lipid components to study skin barrier function, develop lipid-based delivery systems, or create high-performance skincare products.

Application

• Cosmetic & Skincare Formulations: As a key active ingredient in moisturizers, serums, and creams to reinforce the skin's natural lipid barrier, improve hydration, and enhance skin elasticity.
• Lipidomics & Biomedical Research: As a standard or reagent for studying sphingolipid metabolism, cell signaling pathways, and membrane biology in academic and pharmaceutical R&D.
• Drug Delivery Systems: Utilized in the development of liposomes, niosomes, and other lipid nanoparticles for targeted and sustained release of active pharmaceutical ingredients.
• Model Membrane Studies: Incorporated into artificial lipid bilayers and vesicles to investigate membrane properties, protein-lipid interactions, and permeability.
• Hair Care Products: Incorporated into conditioners and treatments to help restore lipid content, improve hair strength, and enhance shine.
• Reference Standard: Serves as a high-purity analytical standard for quality control and quantification in HPLC, LC-MS, and other chromatographic methods.

Basic Information

Product Name	C8 L-Threo Ceramide (D18:1/8:0)
CAS No.	175892-44-1
Molecular Formula	C26H51NO3
Molecular Weight	425.69 g/mol
Synonyms	N-Octanoyl-D-erythro-sphingosine; N-Octanoylsphingosine; Ceramide (d18:1/8:0); N-(Octanoyl)-sphing-4-enine; L-Threo-C8-Ceramide; C8 Ceramide (D18:1/8:0); N-C8:0-Ceramide (d18:1); (2S,3R,4E)-2-Octanamido-4-octadecene-1,3-diol
EINECS	Contact for details

Quality Control

Our C8 L-Threo Ceramide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and formulation. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For long-term storage, keep containers sealed under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.