Description

C8 D-Threo Ceramide (D18:1/8:0) is a high-purity, synthetic ceramide analog with a defined sphingoid base and fatty acid chain length. This compound is critical for advanced research and development in lipid biochemistry and skin biology, serving as a key reference standard and active ingredient precursor. It is primarily utilized by R&D scientists and formulators in the pharmaceutical, cosmetic, and life science industries for studying lipid metabolism, developing topical therapeutics, and creating high-performance skincare formulations.

Application

• Biomedical Research: Used as a critical reference standard and substrate in studies of sphingolipid metabolism, cell signaling pathways, and apoptosis.
• Cosmetic Science & Skincare: Serves as a key intermediate or active ingredient in the development of advanced moisturizers, barrier repair creams, and anti-aging formulations to mimic natural skin lipids.
• Pharmaceutical Development: Employed in the R&D of topical drug delivery systems and dermatological treatments targeting skin barrier disorders.
• Analytical Chemistry: Essential as a certified reference material (CRM) for the qualitative and quantitative analysis of ceramides using techniques like HPLC, LC-MS, and GC-MS.
• Biochemical Reagent: Used in enzymatic assays and in vitro studies to investigate the role of specific ceramide species in biological membranes.
• Nutraceuticals: Potential application in the research of lipid-based supplement formulations, though specific regulatory approval is required.

Basic Information

Product Name	C8 D-Threo Ceramide (D18:1/8:0)
CAS No.	175892-43-0
Molecular Formula	C26H51NO3
Molecular Weight	425.69 g/mol
Synonyms	N-Octanoyl-D-erythro-sphingosine; D-erythro-C8-Ceramide; N-Octanoylsphingosine; (2S,3R,4E)-2-Octanamido-4-octadecene-1,3-diol; Ceramide (d18:1/8:0); C8 Ceramide (D-erythro); N-C8:0-Ceramide (d18:1); Sphingosine, N-octanoyl-, D-erythro- isomer
EINECS	Contact for details

Quality Control

Our C8 D-Threo Ceramide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for structural confirmation, and specific optical rotation to ensure stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with in-house specifications suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the sealed container under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.