Description

Pyrrolo[1,2-A]Pyrazine-4-Carboxylic Acid, Octahydro-1-Oxo-, (4S-Trans)- (9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical chiral intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, enabling new routes to fused heterocyclic systems.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for electronics and material science.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-4-Carboxylic Acid, Octahydro-1-Oxo-, (4S-Trans)- (9Ci)
CAS No.	175233-04-2
Molecular Formula	C8H12N2O3
Molecular Weight	184.19 g/mol
Synonyms	(4S-trans)-Octahydro-1-oxopyrrolo[1,2-a]pyrazine-4-carboxylic acid; (4S-trans)-1-Oxo-octahydropyrrolo[1,2-a]pyrazine-4-carboxylic acid; Pyrrolo[1,2-a]pyrazine-4-carboxylic acid, octahydro-1-oxo-, (4S-trans)-; (4S,8aS)-Octahydro-1-oxopyrrolo[1,2-a]pyrazine-4-carboxylic Acid; 175233-04-2; (4S-trans)-1-Oxo-1,2,3,4,6,7,8,8a-octahydropyrrolo[1,2-a]pyrazine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-A]Pyrazine-4-Carboxylic Acid, Octahydro-1-Oxo-, (4S-Trans)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure consistency and compliance with research and cGMP-grade standards. A detailed Certificate of Analysis (COA) providing identity, assay, chiral purity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic; handle and store under an inert atmosphere (e.g., nitrogen) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.