Description

Polyethylene Glycol 5'000 Monomethyl is a high-purity, monofunctional methoxy-terminated polyether derivative of polyethylene glycol. This compound is a critical functional polymer and chemical intermediate, valued for its precise molecular weight, low polydispersity, and reactive terminal hydroxyl group. It is essential for manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors requiring controlled polymer conjugation, surface modification, and advanced material synthesis.

Application

• Pharmaceutical Conjugation: A key starting material for creating PEGylated drugs, proteins, and peptides to enhance solubility, stability, and circulation time.
• Biomaterial and Hydrogel Synthesis: Used as a macromonomer or cross-linker in the development of biocompatible hydrogels for drug delivery and tissue engineering.
• Surface Functionalization: Employed to create non-fouling, hydrophilic coatings on medical devices, sensors, and nanoparticles.
• Polymer Chemistry Intermediate: Serves as a macroinitiator or building block for synthesizing block copolymers and complex polymer architectures.
• Analytical Chemistry: Utilized as a standard in gel permeation chromatography (GPC) and for modifying separation media.
• Lubricants and Release Agents: Functions as a component in specialized lubricants and mold release agents for industrial processes.

Basic Information

Product Name	Polyethylene Glycol 5'000 Monomethyl
CAS No.	175172-61-9
Molecular Formula	CnH2n+2O(n+1) (n~113) / Typically represented as CH3O-(CH2CH2O)n-H
Molecular Weight	~5,000 g/mol (nominal)
Synonyms	mPEG 5000; Methoxy PEG 5000; Monomethoxy Polyethylene Glycol 5000; Poly(ethylene glycol) methyl ether (Mn ~5000); PEG Monomethyl Ether 5000; α-Methoxy-ω-hydroxy-poly(oxy-1,2-ethanediyl); 2-Methoxyethanol homopolymer; O-Methylpolyethylene glycol; Polyoxyethylene monomethyl ether
EINECS	Contact for details

Quality Control

Our Polyethylene Glycol 5'000 Monomethyl is produced under strict quality management systems. Each batch is characterized to ensure compliance with critical parameters such as molecular weight distribution (polydispersity index), functionality, and absence of impurities. Certificates of Analysis (COA) providing detailed results for identity, assay, and purity are available upon request. We support cGMP manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White waxy solid or flakes
Identification (IR)	Conforms
Assay (Content of mPEG)	≥ 95.0%
Average Molecular Weight (Mn)	4,800 - 5,200
Polydispersity Index (PDI)	≤ 1.05
Methoxy Group Content	Conforms to theoretical value
Water Content (KF)	≤ 1.0%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.