Description

5-Cyclopropyl-2H-Pyrazol-3-Ylamine is a high-purity, versatile pyrazole derivative building block essential for advanced organic synthesis. This compound is valued for its unique cyclopropyl-substituted pyrazole core, which imparts specific steric and electronic properties critical for developing novel active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, lead optimization, and the creation of new chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor programs and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial R&D for constructing complex heterocyclic libraries and exploring structure-activity relationships (SAR).
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or functional organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	5-Cyclopropyl-2H-Pyrazol-3-Ylamine
CAS No.	175137-46-9
Molecular Formula	C6H9N3
Molecular Weight	123.16 g/mol
Synonyms	3-Amino-5-cyclopropyl-1H-pyrazole; 5-Cyclopropyl-1H-pyrazol-3-amine; 5-Cyclopropyl-3-pyrazolamine; 5-Cyclopropyl-2H-pyrazol-3-amine; 1H-Pyrazol-3-amine, 5-cyclopropyl-; 5-Cyclopropyl-3-aminopyrazole; 3-Amino-5-cyclopropylpyrazole
EINECS	Contact for details

Quality Control

Every batch of 5-Cyclopropyl-2H-Pyrazol-3-Ylamine is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.