Description

4-[(4-Aminophenyl)Sulfonyl]Piperazine-2,6-Dione is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. Its core value lies in its bifunctional structure, featuring both a reactive sulfonamide and a diketopiperazine moiety, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Protease Inhibitor Synthesis: Serves as a core scaffold or precursor in the development of protease inhibitors due to its diketopiperazine structure.
• Advanced Material Precursor: Potential use in creating specialized polymers or ligands with specific binding properties.
• Bioconjugation Chemistry: The reactive amine and sulfonyl groups allow for use in linking molecules for diagnostic or therapeutic applications.

Basic Information

Product Name	4-[(4-Aminophenyl)Sulfonyl]Piperazine-2,6-Dione
CAS No.	175136-48-8
Molecular Formula	C10H11N3O4S
Molecular Weight	269.28 g/mol
Synonyms	4-(4-Aminobenzenesulfonyl)piperazine-2,6-dione; 1-(4-Aminophenylsulfonyl)-2,6-piperazinedione; 4-Aminophenyl sulfonyl diketopiperazine; 4-[(4-Aminophenyl)sulfonyl]-2,6-piperazinedione; 4-(4-Aminophenylsulfonyl)-2,6-diketopiperazine; 175136-48-8; AKOS BRN 0977; AS-56200
EINECS	Contact for details

Quality Control

Our 4-[(4-Aminophenyl)Sulfonyl]Piperazine-2,6-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, and residual solvents is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.