Description

1,2-Didocosahexaenoyl-3-Oleoyl Glycerol is a structured triglyceride (TAG) of significant biochemical interest, featuring a unique combination of ω-3 docosahexaenoic acid (DHA) and monounsaturated oleic acid (OA) esterified to the glycerol backbone. This specific molecular architecture is engineered to mimic natural lipid profiles, offering a high-value building block for advanced nutritional and pharmaceutical formulations. It is primarily sought by researchers and manufacturers in the nutraceutical, lipid-based drug delivery, and infant formula sectors for its potential to enhance bioavailability and provide targeted fatty acid delivery.

Application

• Pharmaceutical Excipient: As a key lipid component in self-emulsifying drug delivery systems (SEDDS) and lipid nanoparticles to improve the solubility and absorption of poorly water-soluble active pharmaceutical ingredients (APIs).
• Advanced Nutritional Supplement: A premium ingredient in high-end ω-3 supplements and medical nutrition products designed for targeted fatty acid supplementation and metabolic support.
• Infant Formula Research: Used in R&D to develop next-generation infant formulas that more closely replicate the complex lipid structure of human breast milk.
• Biochemical Research: A critical standard and substrate for studying lipid metabolism, enzyme specificity (e.g., lipases), and membrane biophysics in academic and industrial laboratories.
• Cosmetic Actives Carrier: Employed in high-performance skincare formulations as an emollient and penetration enhancer for active ingredients.
• Model Lipid Compound: Serves as a defined model compound in analytical chemistry for method development and calibration in lipidomics studies.

Basic Information

Product Name	1,2-Didocosahexaenoyl-3-Oleoyl Glycerol
CAS No.	175029-92-2
Molecular Formula	C67H106O6
Molecular Weight	1007.55 g/mol
Synonyms	1,2-Di-DHA-3-OA Glycerol; TAG (DHA, DHA, OA); Glycerol 1,2-didocosahexaenoate 3-oleate; DHA-DHA-OA Triglyceride; Triacylglycerol 22:6(n-3)/22:6(n-3)/18:1(n-9); Oleoyl-didocosahexaenoyl-glycerol; Structured Lipid DHA/DHA/OA
EINECS	Contact for details

Quality Control

Every batch of 1,2-Didocosahexaenoyl-3-Oleoyl Glycerol is manufactured and analyzed under strict quality management systems. We employ advanced chromatographic techniques (HPLC, GC) to ensure high positional purity and chemical identity. Certificates of Analysis (COA) detailing assay, impurity profile, and oxidative stability parameters are provided with each shipment. Our production adheres to cGMP guidelines suitable for pharmaceutical and nutraceutical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oily liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Positional Purity (sn-1,2 DHA; sn-3 OA)	≥ 90.0%
Peroxide Value	≤ 5.0 meq/kg
Anisidine Value	≤ 20.0
Total Oxidation (TOTOX) Value	≤ 26.0
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.