Description

1-Boc-4-(2-Formylphenyl)Piperazine is a high-purity, protected piperazine derivative featuring a formylphenyl substituent, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Chemistry: Integral for introducing piperazine and aromatic aldehyde functionalities into peptide-like structures to modulate biological activity.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	1-Boc-4-(2-Formylphenyl)Piperazine
CAS No.	174855-57-3
Molecular Formula	C16H22N2O3
Molecular Weight	290.36 g/mol
Synonyms	1-Boc-4-(2-Formylphenyl)piperazine; tert-Butyl 4-(2-formylphenyl)piperazine-1-carboxylate; 4-(2-Formylphenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(2-formylphenyl)piperazine; N-Boc-4-(2-formylphenyl)piperazine; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)benzaldehyde; 174855-57-3; Boc-2-formylphenylpiperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(2-Formylphenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.