Description

n-(5-Bromopyrazin-2-Yl)Acetamide is a high-purity brominated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive halogen site and a protected amine functionality, enabling the construction of complex heterocyclic scaffolds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides that require pyrazine-based structures.
• Material Science: Building block for creating specialized ligands, organic semiconductors, and photoactive materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Chemical Biology: Useful for synthesizing molecular probes and tagged compounds for biochemical studies.

Basic Information

Item	Detail
Product Name	n-(5-Bromopyrazin-2-Yl)Acetamide
CAS No.	174680-67-2
Molecular Formula	C6H6BrN3O
Molecular Weight	216.04 g/mol
Synonyms	N-(5-Bromopyrazin-2-yl)acetamide; 2-Acetamido-5-bromopyrazine; Acetamide, N-(5-bromo-2-pyrazinyl)-; 5-Bromo-2-acetamidopyrazine; 174680-67-2; 5-Bromopyrazin-2-amine, N-acetyl-; N-Acetyl-5-bromopyrazin-2-amine
EINECS	Contact for details

Quality Control

Every batch of n-(5-Bromopyrazin-2-Yl)Acetamide is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.