Description

2-Amino-3-(Phenylmethyl)-5-Bromopyrazine is a specialized brominated pyrazine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and bromo functional groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyrazine core.
• Material Science: Building block for creating specialized ligands, catalysts, and organic electronic materials.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) facilitated by the bromine atom.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	2-Amino-3-(Phenylmethyl)-5-Bromopyrazine
CAS No.	174680-55-8
Molecular Formula	C11H10BrN3
Molecular Weight	264.12 g/mol
Synonyms	5-Bromo-3-benzylpyrazin-2-amine; 3-Benzyl-5-bromopyrazin-2-amine; 2-Amino-3-benzyl-5-bromopyrazine; 5-Bromo-3-(phenylmethyl)-2-pyrazinamine; (5-Bromopyrazin-3-yl)methylbenzene-2-amine; 174680-55-8; 2-Pyrazinamine, 5-bromo-3-(phenylmethyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-3-(Phenylmethyl)-5-Bromopyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.