Description

Piperidine, 1-(2-Fluoro-3-Methyl-1-Oxo-4-Pentenyl)-, (R*,R*)- (9Ci) is a specialized chiral piperidine derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which incorporates both a fluorinated ketone and a defined stereochemistry, making it a critical building block for constructing complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals where precise stereochemistry is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the fluorinated moiety can enhance biological activity and metabolic stability.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a model substrate in the development of new catalytic systems for stereoselective synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in medicinal chemistry and synthetic methodology.

Basic Information

Product Name	Piperidine, 1-(2-Fluoro-3-Methyl-1-Oxo-4-Pentenyl)-, (R*,R*)- (9Ci)
CAS No.	174649-72-0
Molecular Formula	C11H18FNO2
Molecular Weight	215.27 g/mol
Synonyms	1-(2-Fluoro-3-methyl-1-oxo-4-penten-1-yl)piperidine; (R*,R*)-1-(2-Fluoro-3-methyl-1-oxopent-4-en-1-yl)piperidine; 1-(2-Fluoro-3-methyl-1-oxo-4-pentenyl)piperidine; 174649-72-0; (R*,R*)-rel-1-(2-Fluoro-3-methyl-1-oxo-4-pentenyl)piperidine; Piperidine, 1-(2-fluoro-3-methyl-1-oxo-4-pentenyl)-, (R*,R*)-rel-; (rel-(R,R))-1-(2-Fluoro-3-methyl-1-oxo-4-pentenyl)piperidine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols, ensuring batch-to-batch consistency and high purity essential for sensitive synthetic applications. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support development projects with custom purity grades and specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.