Description

1-[(tert-Butyl)Oxycarbonyl]-3-(4-Chlorobenzyl)Piperidine-3-Carboxylic Acid is a high-purity, protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical candidates and bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry and peptide mimetic development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Scaffold: Used to construct non-peptide compounds that mimic the structure and function of natural peptides for enhanced stability and bioavailability.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Custom Synthesis Building Block: Sourced by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) group is utilized for the temporary protection of amines during multi-step synthetic sequences.
• Chemical Library Development: Used in the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1-[(tert-Butyl)Oxycarbonyl]-3-(4-Chlorobenzyl)Piperidine-3-Carboxylic Acid
CAS No.	174606-16-7
Molecular Formula	C18H24ClNO4
Molecular Weight	353.84 g/mol
Synonyms	3-(4-Chlorobenzyl)-1-[(tert-butoxy)carbonyl]piperidine-3-carboxylic acid; 1-Boc-3-(4-chlorobenzyl)piperidine-3-carboxylic acid; 1-N-Boc-3-(4-chlorobenzyl)nipecotic acid; 3-(4-Chlorobenzyl)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid; 1-(tert-Butoxycarbonyl)-3-(4-chlorobenzyl)piperidine-3-carboxylic acid; 3-(p-Chlorobenzyl)-1-Boc-piperidine-3-carboxylic acid; (3R/S)-1-(tert-Butoxycarbonyl)-3-(4-chlorobenzyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[(tert-Butyl)Oxycarbonyl]-3-(4-Chlorobenzyl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.