Description

1-o-1'-(Z)-Octadecenyl-2-Hydroxy-Sn-Glycero-3-Phosphoethanolamine CAS NO 174062-73-8 is a high-purity synthetic phospholipid, specifically a lyso-phosphatidylethanolamine derivative. This compound is a critical building block in advanced lipid-based formulations, valued for its unique amphiphilic structure and role in modulating membrane properties. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors developing next-generation drug delivery systems, liposomal formulations, and biomimetic membranes.

Application

• Liposomal Drug Delivery Systems: A key excipient for formulating stable liposomes to enhance the solubility, bioavailability, and targeted delivery of active pharmaceutical ingredients (APIs).
• Biomimetic Membrane Research: Used in the creation of model cell membranes (e.g., supported lipid bilayers) for studying membrane-protein interactions, permeability, and cellular processes.
• Diagnostic Reagents: Incorporated into lipid-based reagents and kits for clinical diagnostics and biomedical research applications.
• Cosmetic & Dermal Formulations: Acts as a high-performance emollient and penetration enhancer in premium skincare products for improved skin barrier function and active ingredient delivery.
• Cell Culture & Biotechnology: Serves as a lipid supplement in serum-free media and for creating specialized lipid nanoparticles (LNPs) beyond mRNA delivery.
• Material Science: A precursor for synthesizing more complex phospholipids or for creating functionalized surfaces with specific biological properties.

Basic Information

Product Name	1-o-1'-(Z)-Octadecenyl-2-Hydroxy-Sn-Glycero-3-Phosphoethanolamine
CAS No.	174062-73-8
Molecular Formula	C23H48NO7P
Molecular Weight	481.60 g/mol
Synonyms	1-O-(9Z-Octadecenyl)-2-hydroxy-sn-glycero-3-phosphoethanolamine; Lyso-PE (18:1); 1-Oleyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; 1-(9Z-Octadecenyl)-2-hydroxy-sn-glycero-3-phosphoethanolamine; (2R)-2-Hydroxy-3-[(9Z)-octadec-9-enoxy]propyl 2-aminoethyl hydrogen phosphate; Lyso-phosphatidylethanolamine (18:1); LPE (18:1); 1-O-Octadecenyl-2-lyso-sn-glycero-3-phosphoethanolamine
EINECS	Contact for details

Quality Control

Our 1-o-1'-(Z)-Octadecenyl-2-Hydroxy-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below for long-term stability. For short-term use, store desiccated at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Peroxide Value	≤ 5.0 meq/kg
Solubility	Soluble in chloroform, methanol; forms micelles in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.