Description

n-((4-Nitrophenyl)Sulfonyl)-1-(tert-Butyloxycarbonyl)Piperazine is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual functional groups, which allow for selective deprotection and further functionalization under controlled conditions. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its sulfonyl and protected amine functionalities.
• Peptidomimetics & PROTACs: Serves as a versatile linker or core structure in the design of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs).
• Material Science Research: Employed in the synthesis of specialty polymers and functional materials requiring specific amine-based chemistry.
• Chemical Biology Probes: Acts as a precursor for fluorescent tags or affinity probes used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	n-((4-Nitrophenyl)Sulfonyl)-1-(tert-Butyloxycarbonyl)Piperazine
CAS No.	173951-83-2
Molecular Formula	C15H21N3O6S
Molecular Weight	371.41 g/mol
Synonyms	1-Boc-4-(4-Nitrobenzenesulfonyl)piperazine; tert-Butyl 4-[(4-nitrophenyl)sulfonyl]piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4-nitrophenylsulfonyl)piperazine; 4-Nitrobenzenesulfonylpiperazine-1-carboxylic acid tert-butyl ester; Boc-piperazine-4-nosylate; N-Boc-4-nosylpiperazine; 1-N-Boc-4-(4-nitrophenylsulfonyl)piperazine; Piperazine, 1-[(1,1-dimethylethoxy)carbonyl]-4-[(4-nitrophenyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters are available upon request. We adhere to a quality management system to ensure traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.