Description

Methyl 3-Iodopyrazine-2-Carboxylate is a high-purity iodinated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile halogenated heterocyclic scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing functionalized pyrazine cores.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to introduce iodine for further functionalization via cross-coupling reactions.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides that utilize heterocyclic chemistry.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a core structure in material science applications.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological systems due to the reactivity of the iodine atom.

Basic Information

Product Name	Methyl 3-Iodopyrazine-2-Carboxylate
CAS No.	173290-17-0
Molecular Formula	C6H5IN2O2
Molecular Weight	264.02 g/mol
Synonyms	3-Iodopyrazine-2-carboxylic acid methyl ester; Methyl 3-iodo-2-pyrazinecarboxylate; 2-Pyrazinecarboxylic acid, 3-iodo-, methyl ester; 3-Iodo-2-pyrazinecarboxylic acid methyl ester; Methyl 3-iodopyrazine-2-carboxylate; 173290-17-0; Methyl 3-iodo-2-pyrazinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Iodopyrazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.